The core human microbiome

Maternal transfer of core microorganisms

It is well-established that numerous disease states are correlated with imbalances in the gut microbiota and with diseases of the microbiota. Indeed, Human Microbiology Institute’s members have discovered that the human microbiota contains core microorganisms, and that this core is maternally inherited. The HMI is currently conducting unique research to uncover the effects of particularities in the inheritance and maternal transfer of the microbiome in human heath and diseases.

Microbiota/mitochondria cross-talk

Our research in this area is based on the “Maternal inheritance of microbiota” theory and to is designed to enhance our understanding of the specific interactions and cross-talk that occur between the microbiota and mitochondria, and to thereby expand our understanding of mitochondrial diseases. Furthermore, our research is dedicated to revealing the particularity of the inheritance of the microbiota within families, and the impact that this inherited microbiome has over the coarse of an individual’s lifespan.

Newly discovered problems

The results of these studies will lead to a better understanding of which bacteria species and strains are passed from one generation to another within a family and how, as well as how these organisms interact with human mitochondria and the effects that they have on health, diseases, the spreading of antibiotic resistance, and on the individual particularities of development, including the development of individuals within certain ethnic groups.

New insights

Discoveries made by the HMI will provide new insights and perspectives towards the study, prevention, and treatment of microbiota associated diseases and will open new doors for studying microbiota-mitochondria and microbiota-inherited diseases.