Kluyvera intestini GT-16

Kluyvera intestini GT-16 in Patients with Gastric Cancer

It is commonly known that gut microbes contribute to cancer development,which is why the discovery of previously unknown bacterial species in the stomach of the patient with gastric cancer is so significant.

Kluyvera intestini GT-16 is a novel species that needs to be studied in terms of its role in cancer progression. Genetic analyses indicated that Kluyvera intestini GT-16 harbors numerous antibiotic resistance genes and a variety of toxin-encoding genes, including hemolysin, nucleases and numerous peptidases.

HMI will perform next level studies to examine the role of Kluyvera intestini GT-16 in gastrointestinal malignancies.

In future research, we intend to determine the prevalence of Kluyvera intestini GT-16 among different cancer patient groups and to evaluate its possible link to the cancerogenicity.

CITATION

Tetz, G., & Tetz, V. (2016). Draft Genome Sequence of Kluyvera intestini Strain GT-16 Isolated from the Stomach of a Patient with Gastric Cancer. Genome Announcements, 4(6), e01432-16.

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Draft Genome Sequence of Kluyvera intestini Strain GT-16 Isolated from the Stomach of a Patient with Gastric Cancer

Publication Type JournalArticle
Authors George Tetz
Victor Tetz
Abstract Here, we report the complete genome sequence of the novel, non-spore-forming Kluyvera intestini strain GT-16, isolated from the stomach of a patient with gastric cancer. The genome is 5,868,299 bp in length with a GC content of 53.0%. It possesses 5,350 predicted protein-coding genes encoding virulence factors and antibiotic resistance proteins.
Year of Publication 2016
Journal Genome announcements
DOI 10.1128/genomeA.01432-16