Antimicrobial resistance/Microbiological hazards for humans

Each of us is surrounded by and interacts with trillions of microorganisms each day, including bacteria, fungi, and viruses. To minimize the risk of these interactions to human health is one of the primary goals of the Human Microbiology Institute. Based on our research, we develop algorithms and approaches for the prevention of diseases associated with exposure to microorganisms and their spores within the environment (water, food, and air, and exposure to public places) on an individual and microbiota-specific basis.

Antibiotics have saved millions of lives worldwide; however, due to increased rates of antimicrobial resistance, these drugs are losing their effectiveness. As such, the problem of antibiotic resistance has been widely discussed in recent years, with reports from the Review on Antimicrobial Resistance estimating that medicine-resistant infections will claim more lives annually than cancer by the year 2050. Indeed, according to this important scientific journal, deaths caused by drug resistance will rise from 700,000 in 2015 to an estimated 10 million per year in 2050 in the United States alone.

Data Regarding Antibiotic Resistance
  • Recognized as one of the biggest challenges facing human health.
  • The emergence of antibiotic resistance is occurring at a faster rate than that for the development of novel antibiotics.
  • More than 2 million patients in the US develop hospital-acquired infections annually, the vast majority of which are due to antibacterial-resistant species.
  • Greater than 700,000 deaths are caused by drug resistant microorganisms in the US each year.

Today, the majority of people are concentrated in urban areas with numerous common areas that are characterized by high population densities. As a result, the widespread use of antimicrobials and antiseptics has led to the selective breeding and spread of resistant strains. In addition, such crowded areas facilitate the accumulation of microorganisms and their distribution among humans.

Our goals

The goals of Human Microbiology Institute include the development and improvement of methods for antimicrobial usage in order to:

  • Overcome antibiotic resistance
  • Prevent the spread of pathogenic species of bacteria and fungi that are resistant to antibiotics
  • Prevent the spread of pathogenic species of bacteria and fungi that are resistant to sanitizers and disinfectants
  • Develop a method for fighting some of the most dangerous bacterial and fungal pathogens that have grown resistant to drugs currently on the market.

In vitro antimicrobial activity of a novel compound, Mul-1867, against clinically important bacteria.

Antimicrobial resistance and infection control (2015)

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Antimicrobial activity of Mul-1867, a novel antimicrobial compoud, against multidrug-resistant Pseudomonas aeruginosa.

Annals of Clinical Microbiology and Antimicrobials (2016)

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