Bacillus obstructivus VT-16-70 in Patients with Chronic Obstructive Pulmonary Diseases
Chronic lower respiratory disease, primarily COPD, was the third leading cause of death in the United States in 2014. Almost 15.7 million Americans (6.4%) reported that they have been diagnosed with COPD.
Bacillus obstructivusVT-16-70is a novel species that needs to be studied in terms of its role in COPD exacerbation. Genetic analyses indicated that Bacillus obstructivusVT-16-70harbors numerous antibiotic resistance genes and a variety of toxin-encoding genes, including hemolysin, nucleases and numerous peptidases.
HMI will perform next level studies to examine the role of Bacillus obstructivusVT-16-70in COPD and other lung infections.
In future research, we intend to determine the prevalence of Bacillus obstructivus VT-16-70 among different patient groups and to evaluate its possible link to the exacerbations of COPD.
Tetz G, Tetz V. 2017. Draft Genome Sequence of Bacillus obstructivus VT-16-70 Isolated from the Bronchoalveolar Lavage Fluid of a Patient with Chronic Obstructive Pulmonary Disease. Genome Announc5:e01754-16. doi: 10.1128/genomeA.01754-16.