Bacillus obstructivus VT-16-70

Bacillus obstructivus VT-16-70 in Patients with Chronic Obstructive Pulmonary Diseases

Chronic lower respiratory disease, primarily COPD, was the third leading cause of death in the United States in 2014. Almost 15.7 million Americans (6.4%) reported that they have been diagnosed with COPD.

Bacillus obstructivusVT-16-70is a novel species that needs to be studied in terms of its role in COPD exacerbation. Genetic analyses indicated that Bacillus obstructivusVT-16-70harbors numerous antibiotic resistance genes and a variety of toxin-encoding genes, including hemolysin, nucleases and numerous peptidases.

HMI will perform next level studies to examine the role of Bacillus obstructivusVT-16-70in COPD and other lung infections.

In future research, we intend to determine the prevalence of Bacillus obstructivus VT-16-70 among different patient groups and to evaluate its possible link to the exacerbations of COPD.

CITATION

Tetz G, Tetz V. 2017. Draft Genome Sequence of Bacillus obstructivus VT-16-70 Isolated from the Bronchoalveolar Lavage Fluid of a Patient with Chronic Obstructive Pulmonary Disease. Genome Announc5:e01754-16. doi: 10.1128/genomeA.01754-16.

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Draft Genome Sequence of Bacillus obstructivus VT-16-70 Isolated from the Bronchoalveolar Lavage Fluid of a Patient with Chronic Obstructive Pulmonary Disease

PublicationType JournalArticle
Authors George Tetz
Victor Tetz
Abstract We report here the draft genome sequence of Bacillus obstructivus VT-16-70, a novel spore-forming bacterium isolated from the lungs of a patient with chronic obstructive pulmonary disease. The genome comprised 5,220,753 bp, with 35.2% GC content. There were 4,972 predicted protein-coding genes, including those associated with antibiotic resistance and virulence. -coding genes encoding virulence factors and antibiotic resistance proteins.
Year of Publication 2017
Journal Genomeannouncements
DOI 10.1128/genomeA.01754-16