The Human Microbiology Institute is delighted to introduce a novel group of human diseases: “microbiota diseases”. The term “microbiota diseases” reflects the primary and crucial role of microbiota-related disorders in certain host organism pathologies.
HMI research indicates that microbiota diseases lead to pathologies in the macroorganism, including increased intestinal permeability and leaky gut- associated pathologies.
Intestinal barrier dysfunction or disruption of the intestinal barrier, known as “leaky gut” syndrome, is characterized by increased transcellular permeability or increased permeability of the tight junctions to macromolecules. This abnormally permeable mucosal barrier is associated with various disease pathologies, including:
- Inflammatory bowel disease
- Crohn’s disease
- Alzheimer’s disease
- Amyotrophic lateral diseases
- Parkinson’s disease
- Schizophrenia
- Autism
- Type 1 diabetes
- Cancers
- Cardiovascular disorders
- Rheumatoid arthiritis
- Liver and kidney failure