New group of human viral diseases

The Human Microbiology Institute aims to unmask and characterize the types of diseases that affect and can damage the human microbiota, and to expand our understanding of the role of these diseases and their diagnostic potential in regards to mammalian diseases and lifespan.

Our study demonstrates that increased intestinal permeability may be induced by bacteriophages that affect the microflora. We introduce the novel term “microbiota diseases” to reflect the crucial role of microbiota-related disorders in some host organism pathologies. To our knowledge, this study for the first time indicates the possible link between bacteriophages and mammalian pathologies associated with increased intestinal permeability such as behavioral and psychological disorders or systemic inflammatory and autoimmune disorders. We hypothesize that these pathologies may be contagious due to possible acquired phage infection and development of microbiota diseases. We propose that infection of microbiota by bacteriophages can be considered a new group of viral diseases of mammals including humans.

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We try to make our data available to the whole scientific community. The HMI welcomes collaborative studies to unravel the pathogenesis of human diseases associated with the microbiota. However, we ask that you respect the rights of first publication and cite our work as follows:

Bacteriophage infections of microbiota can lead to leaky gut in an experimental rodent model.